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KMID : 0361620190540060498
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Journal of the Korean Orthopaedic Association
2019 Volume.54 No. 6 p.498 ~ p.508
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Spinal Cord Injury and Neuro-Regeneration
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Ahn Joo-Hyun
Park Hyung-Youl
Kim Young-Hoon
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Abstract
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Recent advances in the understanding of the pathophysiology of spinal cord injury (SCI) and new therapeutic approaches have provided promising results for this incurable and debilitating central nervous system injury. Various neuro-protective and neuro-regenerative trials have been attempted to overcome SCIs. This review summarizes the reported experimental and clinical data regarding neuro-regenerative trials with the proven pathophysiology of SCI. In addition, the prerequisites for safe and effective clinical trials are discussed.
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KEYWORD
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spinal cord injuries, neuroprotection, spinal cord regeneration, cell-and tissue-based therapy
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